Steroid-hormone
نویسندگان
چکیده
منابع مشابه
I-34: Steroid Hormone Signalling at the FetomaternalInterface
Background: Progesterone is indispensable for differentiation of human endometrial stromal cells (HESCs) into decidual cells, a process that critically controls embryo implantation. However, HESCs also abundantly express androgen receptors (AR), yet the role of this member of the superfamily of ligand-dependent transcription factors in the decidual process remains poorly elucidated. Materials a...
متن کاملSteroid hormone receptors: an update.
Steroid hormones (SHs) are lipophilic molecules derived from cholesterol and synthesized in the adrenal cortex (glucocorticoids, mineralocorticoids, and adrenal androgens), the testes (testicular androgens, oestrogen), and the ovary and placenta (oestrogens and progestagens or progestins). SHs reach their target cells via the blood, where they are bound to carrier proteins, and because of their...
متن کاملPlasma steroid-binding proteins: primary gatekeepers of steroid hormone action
Biologically active steroids are transported in the blood by albumin, sex hormone-binding globulin (SHBG), and corticosteroid-binding globulin (CBG). These plasma proteins also regulate the non-protein-bound or 'free' fractions of circulating steroid hormones that are considered to be biologically active; as such, they can be viewed as the 'primary gatekeepers of steroid action'. Albumin binds ...
متن کاملRegulation of steroid hydroxylase gene expression and steroid hormone biosynthesis.
In our test system, the action of glucagon o n steroid oxidation follows a dose-response relationship similar to its actions on diacylglycerol generation and not on cyclic AMP generation [ 171. The fact that it does not act via activation of adenylate cyclase and generation of cyclic AMP was proved by the usc of I-N-a-trinitrophenylhistidine12-homoarginine glucagon (TH)-glucagon, an analogue of...
متن کاملSteroid hormone mediated regulation of corticotropin-releasing hormone gene expression.
Corticotropin-releasing hormone (CRH), a 41 amino acid polypeptide, is expressed in many regions of central nervous system and peripheral tissues and mediates many physiological functions. Abnormal production of CRH is involved in some pathological processes. Among various endogenous factors that modulate CRH production, steroid hormones control CRH production by regulating its gene transcripti...
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ژورنال
عنوان ژورنال: FEBS Letters
سال: 1978
ISSN: 0014-5793
DOI: 10.1016/0014-5793(78)81222-8